Application Server Administration job failed for service instance. Event ID 6482

There were many issues that require you to clear the share point configuration cache on your servers.

Below is the step by step provided by Microsoft for Clearing Configuration Cache
1. Stop the Windows SharePoint Services Timer service (Found in Windows Services)
2. Navigate to the cache folder
Drive:\ProgramData\Microsoft\SharePoint\Config\<GUID>
There may be more than one  GUID folders
3. Locate the folder that has the file "Cache.ini"
4. Back up the Cache.ini file.
5. Delete all the XML configuration files in the GUID folder
Note : make sure that you do not delete the GUID folder and the Cache.ini file that is located in the GUID folder.
6. Open Cache.ini file in Note Pad, click Select All and Delete. Type 1, and then Save. Close the Note Pad.
7. Start the Windows SharePoint Services Timer service
8. Restart IIS
Make sure that the Cache.ini file in the GUID folder now contains its previous value, not 1.